The objective of the 2015 Zarrow Mental Health Symposium was to develop and enhance professional skills and knowledge in the prevention, recognition, assessment and treatment of mental health and substance abuse disorders. Discussion highlighted emerging knowledge, best practices and innovative approaches to integrated care, with emphasis on increased access to appropriate high quality prevention, intervention, treatment, recovery, and wellness services and supports that impact the relationship between health, behavioral health, and spiritual well-being across the life-span, and inclusive of special populations and cultural/ethnic diversity. Ethical considerations were also addressed.